刘虎威 教授，博士生导师
Email: hwliu@pku.edu.cn
分析化学专业
研究方向: 生物分离与检测，主要包括色谱（毛细管电泳）-质谱分析，药物分析，生物与临床分析
中国化学会 会员
中国色谱学会 常务理事
中国化学会色谱专业委员会 副主任
中国物理学会质谱学会 常务理事，有机质谱分专业委员会 主任
北京理化分析测试技术学会 理事，北京色谱专业委员会 副理事长
中国仪器仪表学会分析仪器分会理事，样品前处理专业委员会副主任
国家标准样品技术委员会天然产物国家标准样品工作组组长
《Journal of Separation Science》和《分析仪器》副主编
《Analytical Chemistry》和《Analytical and Bioanalytical Chemistry》编委，以及《化学通报 》、《中国药学. 英文版》、《分析试验室》、《分析科学学报》、《色谱》、《分析测试学报》、《现代科学仪器》、《科学仪器》、《岩矿测试》和《食品安全质量检测技术》编委
简历
1978.10-1982.7 北京理工大学，学士学位
1984.9-1990.7 北京理工大学 硕士，博士学位
1990.8-1993.7 北京大学化学系讲师
1993.8-2001.7 北京大学化学系，副教授
1995.9-1996.7 芬兰赫尔辛基大学化学系 交流学者
1996.7-1997.3 美国普渡大学化学系 BAS公司 交流学者
1999-2001 法国南锡大学 合作研究
2001.8至今 北京大学化学系，教授
2008-2017 北京大学化学与分子工程学院党委书记
2014年-2017年 分析测试中心主任（兼）
教学工作：
a. 讲授研究生课程"高等色谱分析";
b. 讲授本科生课程"色谱分析";
c. 指导硕士研究生、博士研究生及国内进修教师
近年代表性著作：
刘虎威 编著《气相色谱方法及应用》（第二版），化学工业出版社，2007.
刘虎威 主编《色谱技术问答》, 化学工业出版社，2009.
《分析化学教程》，北京大学出版社，2005.（参加编写）
《基础分析化学实验》(第三版)，北京大学出版社, 2009.（参加编写）
Youyou Yang and Huwei Liu, Separation and Determination of Tobacco-Specific N-Nitrosamines, in Fernanda López Marcos and Cristofer Ramírez Ortiz (Ed), Tobacco: Production, Uses and Health Implications, Nova Science Publishers, Inc. 2012, New York
Yi Liu, Yu Bai, and Huwei Liu, Analytical Methodologies of Chitosan in Functional Foods, in Leo M.L. Nollet and Fidel Toldra (Ed), Handbook of Analysis of Active Compounds in Functional Foods, CRC Press, Boca Raton, FL, USA, 2012, p513-544
近年代表性学术论文：
Cuilan Chang, Gege Xu, Yu Bai*, Chengsen Zhang, Xianjiang Li, Min Li, Yi Liu and Huwei Liu*, Online Coupling of Capillary Electrophoresis with Direct Analysis in Real Time Mass Spectrometry, Anal. Chem., 2013, 85 (1): 170–176
Jialing Zhang, Zhigui Zhou, Jianwang Yang, Wei Zhang, Yu Bai * and Huwei Liu, Thin Layer Chromatography/Plasma Assisted Multi-wavelength Laser Desorption Ionization Mass Spectrometry for Facile Separationmand Selective Identification of Low Molecular Weight Compounds, Anal. Chem. 2012, 84(3): 1496–1503，DOI: 10.1021/ac202732y
Zhigui Zhou, Youyou Yang, Jialing Zhang, Zhenxiang Zhang, Yu Bai, Yiping Liao and Huwei Liu*, A Novel Membrane-Based Enzyme Micro-reactor Coupled Online with LC/QTOF MS for Protein Analysis, Anal. Bioanal. Chem., 2012, 403(1): 239-246
Jialing Zhang, Ze Li, Chengsen Zhang, Baosheng Feng, Zhigui Zhou, Yu Bai and Huwei Liu*, Graphite Coated Paper as Substrate for High Sensitive Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry, Anal Chem., 2012, 84 (7): 3296–3301
Yehua Han, Zhigui Zhou, Hongliang Wu, Honggang Nie, Rong Lei, Yu Bai and Huwei Liu*, Determination of jasmonic acid epimers and their epimerization study by chiral liquid chromatography-mass spectrometry, J. Chromatogr. A, 2012, 1235: 125-137
Zhigui Zhou, Jialing Zhang, Jiawei Xing, Yu Bai and Huwei Liu*, Membrane-based Continuous Remover of Trifluoroacetic Acid (TFA) in Mobile Phase for LC-ESI-MS Analysis of Proteins, J. Am. Soc. Mass Spectrom., 2012, 23(7): 1289-1292
Cuilan Chang, Xin Wang, Yu Bai and Huwei Liu*, The applications of nanomaterials in enantioseparation and related techniques, Trend in Anal. Chem., TrAC, 2012, 39: 195–206
Cuilan Chang, Zhigui Zhou, Youyou Yang, Yehua Han, Yu Bai and Huwei liu*, Normal phase HPLC coupled with DART-MS for the chiral analysis of 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol and jasmonic acid, Electrophoresis, 2012, 33(22): 3387–3393
Min Li, Zhigui Zhou, Honggang Nie, Yu Bai and Huwei Liu*, Recent advances of chromatography and mass spectrometry in lipidomics, Anal. Bioanal. Chem., 2011, 399: 243–249
Yi Liu, Xiaofang Fu, Yu Bai, Maolin Zhai, Yiping Liao, Jie Liao and Huwei Liu*, Improvement of reproducibility and sensitivity of CE by using the capillary coated dynamically with carboxymethyl chitosan, Anal. Bioanal. Chem., 2011, 399: 2821–2829
Zhigui Zhou, Jialing Zhang, Wei Zhang, Yu Bai* and Huwei Liu, Rapid screening for synthetic antidiabetic drug adulteration in herbal dietary supplements using direct analysis in real time mass spectrometry, Analyst, 2011, 136 (12): 2613 – 2618
Xiaofang Fu, Yi Liu, Wei Li, Yu Bai, Yiping Liao and Huwei Liu*, Determination of dissociation constants of aristolochic acid I and II by capillary electrophoresis with carboxymethyl chitosan-coated capillary, Talanta, 2011, 85(15): 813–815
Youyou Yang, Cong Yu, Meng Zhou, Ning Li, Jie Liao, Yu Bai and Huwei Liu*, Research on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis, J. Chromatogr. A, 2011, 1218: 6505–6510
Yehua Han, Yu Bai, Yiling Xiao, Fuyou Du, Yuan Liang, Zhijing Tan, Meiping Zhao and Huwei Liu*, Simultaneous discrimination of jasmonic acid stereoisomers in wounded tobacco leaves by CE-QTOF-MS employing the partial filling technique, Electrophoresis, 2011, 32(19): 2693-2699
Yu Bai, Fuyou Du, Youyou Yang, Yu Bai and Huwei Liu*, In-capillary non-covalent labeling and determination of tomato systemin with quantum dots in capillary electrophoresis with laser-induced fluorescence detection, J. Sep. Sci., 2011, 34：2893–2900
Caiqiao Xiong, Xiaoyu Zhou, Rui Chen, Yiming Zhang, Wen-Ping Peng, Zongxiu Nie*, Huan-Cheng Chang, Huwei Liu and Yi Chen, Characterization of Column Packing Materials in High-Performance Liquid Chromatography by Charge-Detection Quadrupole Ion Trap Mass Spectrometry, Anal. Chem., 2011, 83 (13): 5400–5406
Yehua Han, Pavel Levkin, Irene Abarientos, Huwei Liu, Frantisek Svec and Jean Frechet, Monolithic Superhydrophobic Polymer Layer with Photopatterned Virtual Channel for the Separation of Peptides Using Two-Dimensional Thin Layer Chromatography- Desorption Electrospray Ionization Mass Spectrometry, Anal. Chem., 2010, 82: 2520–2528
Honggang Nie, Ranran Liu, Youyou Yang, Yu Bai, Yafeng Guan, Daqing Qian , Tao Wang and Huwei Liu*, Lipid profi ling of rat peritoneal surface layers by online, normal- and reverse-phase 2D LC QToF-MS, J. Lip. Res., 2010, 51: 2833-2844
Youyou Yang, Honggang Nie, Chenchen Li, Yu Bai, Ning Li, Jie Liao and Huwei Liu*，On-line concentration and determination of tobacco-specific N-nitrosamines by cation-selective exhaustive injection-sweeping-micellar electrokinetic chromatography，Talanta, 2010, 82: 1797–1801
Fuyou Du, Yu Bai, Yu Bai and Huwei Liu*, Quantitative Detection of Trace Systemins in Solanaceous Plants by Immunoaffinity Purification combined with LC/ESI QTOF MS, Anal. Chem., 2010, 82: 9374–9383
Zhengxiang Zhang, Bo Yan, Kelin Liu, Yiping Liao and Huwei Liu*, CE-MS analysis of heroin and its basic impurities using charged polymer-protected gold nanoparticles-coated capillary, Electrophoresis, 2009, 30: 379–387
Yi Liu, Xiaofang Fu, Chao Ma, Jiasheng Zhong and Huwei Liu*, Chiral separation of Raltitrexed by cyclodextrin-modified micellar electrokinetic chromatography, Anal. Bioanal. Chem., 2009, 393: 321–326
Nannan Pang, Zhengxiang Zhang and Huwei Liu*, Enantioseparation of zolmitriptan and determination of binding constants and thermodynamic parameters by CD-modified CZE, Anal. Bioanal. Chem., 393 (2009) 313--320
Yu Zhou, Hailin Shen, Tie Yi, Dawei Wen, Nannan Pang, Jie Liao and Huwei Liu*，Synergistic Design of Electric Field and Membrane in Facilitating Continuous Adsorption for Cleanup and Enrichment of Proteins in Direct ESI-MS Analysis，Anal. Chem., 2008, 80: 8920–8929
Zhengxiang Zhang, Bo Yan, Yiping Liao and Huwei Liu*，Nanoparticles: is it promising in capillary electrophoresis? Anal. Bioanal. Chem., 2008, 391: 925-927
Zhengxiang Zhang, Bo Yan, Kelin Liu, Yiping Liao and Huwei Liu*，Separation and fragmentation study of heroin and its basic impurities by reversed-phase liquid chromatography coupled to tandem mass spectrometry, Rapid Commun. Mass Spectrom., 2008, 22: 2851-2862.
Xia Yang, Yan Xia, Chuanjiang. Tao, Yiping Liao, Yumin Zuo and Huwei Liu*, A comparative study of micellar and microemulsion electrokinetic chromatography for the separation of benzoylurea insecticides and their analogues, Electrophoresis, 2007, 28: 1744-1751
Xiaofang Fu, Ling Huang, Fei Gao, Wei Li, Nannan Pang, Maolin. Zhai and Huwei. Liu*, Moutian Wu, Carboxylmethyl chitosan-coated capillary and its application in capillary electrophoresis, Electrophoresis, 2007, 28:1958-1963
Senhua Shi, Wei Li, Yiping Liao and Huwei Liu*, Online Concentration of Aristolochic Acid I and II in Chinese medicine preparation by Micellar Electrokinetic Chromatography, J. Chromatogr A, 2007, 1167: 120-124
Wei Li, Zheng Chen, Yiping Liao and Huwei Liu*, Study on Separation of Aristolochic Acid I and II by Micellar Electrokinetic Capillary Chromatography and Competition Mechanism between SDS and ?-Cyclodextrin, Electrophoresis, 2006, 27: 837-841
Suxuan Gong, Fujia Liu, Wei Li, Fei Gao, Chunjin. Gao, Yiping Liao and Huwei Liu*, Separation of hydrophobic solutes by organic-solvent-based micellar electrokinetic chromatography using cation surfactants, J. Chromatogr. A, 2006, 1121: 274-279
Chenchen Li, Zheng Chen, Dawei Wen, Jianxun Zhang, Bing Yu and Huwei Liu*，Determination of tobacco-specific N-nitrosamines in rabbit serum by capillary zone electrophoresis and capillary electrophoresis-electrospray ionization-mass spectrometry with solid-phase extraction, Electrophoresis, 2006, 27: 2152-2163
Bing Yu, Hailin Cong, Huwei Liu*, Yuanzong Li and Feng Liu, Separation and detection of erythropoietin (EPO) by CE and CE-MS, Trend in Anal. Chem., TrAC, 2005, 24(4): 350-357
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